Embryo donation in St. Petersburg
The classic IVF programme involves the use of the partners' sex cells, which are fertilised in vitro and then cultured, and embryo transfer. However, it is not always possible to use the couple's own embryos. In these cases, such a method of assisted reproductive technologies as transfer of donor embryos is used.
Embryo donation may be used in the following cases:
Absence of partners' own sex cells
High risk of developing inherited diseases
Repeated receipt of poor quality embryos whose transfer does not result in pregnancy (in 3 or more attempts).
Male and female infertility at the same time, as well as female infertility in single women who, for one reason or another, cannot use donor sperm and their own eggs.
What are donor embryos?
Donor embryos are obtained from fresh donor eggs and frozen donor sperm. The embryos grow in IVF lab until the blastocyst stage (within 5-7 days). Blastocysts of good quality are frozen (in some cases, a biopsy of the trophectoderm is taken beforehand for pre-implantation genetic testing of PGT-A). From this point on, the donor embryos can be used in the ART programme: they can be thawed and transferred into the uterus at any time.
In Russia, it is allowed to use the embryos of ex-patients as donor embryos. In our clinic, this is not the case: firstly, donors undergo a more in-depth examination than infertility patients, and secondly, the pregnancy rate when transferring such "patients'" embryos is lower than when transferring donor embryos.
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Types of embryo donation
There are two types of donor embryos at Delta Fertility Cryobank:
Donor embryos without PGT-a
Those that have undergone preimplantation genetic testing for aneuploidies (PGT-A).
This test examines the quantitative set of chromosomes and selects those embryos that carry the correct chromosomes and have a chance of pregnancy. Transferring such embryos has a higher chance of pregnancy than transferring embryos without genetic testing.
The steps of Embryo Adoption programmes:
The first step involves a consultation with a fertility specialist.
At the appointment, the doctor determines whether there are indications for the use of donor embryos and explains the process.
In the second stage, the couple or woman chooses a donor embryo.
There is a convenient online database that specifies the quality of embryos, the PGT-A results, and provides information about the donors. These are donor profiles with childhood photos, blood type and Rh factor, age, ethnicity, eye and hair colour.
Once a donor embryo has been selected, the woman will undergo the medical examination required before undergoing an ART programme.
If the doctor has not identified any contraindications, the endometrium is prepared for the transfer of a thawed embryo (frozen embryo transfer). In Delta Fertility, we recommend a single embryo transfer to reduce the risk of multiple pregnancies and related complications.
Embryo transfer can be performed in a natural cycle (without hormonal preparation or with a minimal one) or after the hormonal therapy.
In both cases, the transfer is performed in the middle of the second half of the menstrual cycle.
On the day of transfer, the embryo is thawed, the embryologist assesses its viability, and then the embryo is placed in the uterine cavity.
After the transfer, it is important to strictly follow the medication regimen prescribed by the fertility specialist.
10-14 days after embryo transfer, the woman takes a blood test for chorionic hormone (hCG). If its level is higher than 50ME/ml, it means that pregnancy has occurred. 21 days after the embryo transfer, the doctor performs the pelvic ultrasound.